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Kashif Khan

The Truth and History Behind the Science of Functional Genomics with Dr. Mansoor Mohammed

JANUARY 16, 2024

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Genetics is the transcript of your own personal health. We often perceive it as something that dictates that health issues are hereditary but the truth is that no one was born with chronic illnesses. In what way should we then perceive and interpret genetics?

In this episode, Dr. Krista Kostroman is joined by Dr. Mansoor Mohammed, PhD. Dr. Mansoor is one of the founding members of The DNA Company as he had committed his life into studying genetics and all fields that revolve around it. He is a recognized authority in the fields of medical genomics and personalized medicine. He is the holder of several patents in the general fields of molecular diagnostics and genomics research. Dr. Mohammed completed his doctoral dissertation at the University of Guelph, Canada, majoring in both Molecular Immunology and Transgenic Technologies. He completed postdoctoral training in Clinical Cytogenetics at both UCLA and Baylor College of Medicine.

Prior to becoming the scientific founder of The DNA Company, Dr. Mohammed co-founded Younique Genomics, served as the President and CEO of CombiMatrix Diagnostics—where he oversaw the development of one of the most comprehensive genomics testing menus in the diagnostic industry—and was the Director of Advanced Technologies at Quest Diagnostics, where he was honored with the Medical Innovation Award, the highest accolade given for excellence in medical research. Prior to his role at Quest Diagnostics, Dr. Mohammed was a founder and Director of Research and Development at Spectral Genomics. At Spectral Genomics, Dr. Mohammed pioneered the development of commercial Comparative Genomic Hybridization (CGH) array technologies and was responsible for the design and launch of the industry’s first commercially available CGH arrays.

Together, Dr. Krista and Dr. Mansoor go through the different stages and understandings of DNA that Dr. Mansoor went through - calling this the four epochs of his career.

During the first epoch, Dr. Mansoor invented this whole genome technology where he studied human antibodies, and looked into animal models in order to deepen the study on the human's genetic makeup. This led him to founding companies such as Spectral Genomics and with the knowledge that they had at that time, they were able to focus on what was broken with the human body and used the study of DNA to find solutions to this. 

Moving on to 2011, he entered the second epoch of his career where he was questioned why they do not delve further than what was broken. This initiated Dr. Mansoor to dive deeper and study genomics with the addition of functional genomics. 

After continually studying what is unknown regarding a person's genomics, then comes the birth of The DNA Company. This story showcases how our clinicians today are able to prevent any possible illness by looking into a person's unique genetic makeup - even down to the body's smallest nuances.

Onto the third epoch, the amount of information gathered must be handled with care so as not to dilute it in a soundbite that suggests that science is binary but rather give science its due right. This was when he realized that there was more to be done and stepped away to focus on studying yet continually serving people.

Lastly, the fourth epoch dives into the study of hormone replacement and the continuous journey of advocating and researching for optimal human health, nutrition, lifestyle, and environment. 

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Keep yourself up to date on The DNA Talks Podcast! 

This episode may also be viewed on YouTube